Thyroid Eye Disease (TED): A Comprehensive, Evidence-Based Update for Clinicians

Definition and Epidemiology Thyroid eye disease (TED), also known as Graves’ orbitopathy (GO) or thyroid-associated orbitopathy (TAO), is an organ-specific autoimmune disorder characterized by inflammation, fibrosis, and expansion of the…

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Lewy Body Dementia (LBD): A Comprehensive Clinical Overview for Physicians

Revised with reference to current diagnostic criteria (2017 Fourth Consensus Report of the DLB Consortium), recent pathophysiological insights, and evidence-based management guidelines (including 2022–2024 updates from the American Academy of…

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Truman Show Delusional Disorder: A Clinical Review Based on Current Evidence

Prepared for Clinicians – Includes Diagnostic Criteria, Epidemiology, Differential Diagnosis, Neurobiological Considerations, and Evidence-Based Management Strategies Definition and Historical Context The term “Truman Syndrome” (or Truman Show Delusion, TSD) refers…

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Hand, Foot, and Mouth Disease (HFMD): A Clinically Detailed Overview for Medical Professionals

Updated per Current Evidence (2023–2024 Guidelines from CDC, WHO, ECDC, and Peer-Reviewed Literature) Etiology & Causative Agents Hand, foot, and mouth disease (HFMD) is a highly contagious, typically acute febrile…

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Fifth Disease

Updated per current CDC, IDSA, and ECDC guidelines (2023–2024); evidence synthesized from peer-reviewed literature including New England Journal of Medicine, Clinical Infectious Diseases, Pediatrics, and The Lancet Infectious Diseases. Etiology…

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Revised Clinical Overview: “Cave Syndrome” – A Non-Formalized Phenomenon of Post-Pandemic Social Reintegration Difficulty

Definition & Clinical Context “Cave syndrome” is not an officially recognized diagnostic entity in either the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) or the…

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Charcot-Marie-Tooth Disease: A Clinically Oriented Overview for Practicing Physicians

Revised with emphasis on pathophysiology, modern classification, diagnostic algorithms, and evidence-based management—updated to 2024 guidelines and literature (including recent trials and consensus statements from the Inherited Neuropathies Consortium, AAN, and…

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