1. Introduction Irinotecan is a topoisomerase I inhibitor widely used in the management of various gastrointestinal malignancies. It is a prodrug metabolized to its active form, SN-38, which exerts cytotoxic…
1. Introduction & Classification Femara (generic name: Letrozole) is a prescription medication classified as an Aromatase Inhibitor (AI), specifically a nonsteroidal, competitive inhibitor of the aromatase enzyme. It is widely…
1. Introduction and Classification Nabumetone is a member of the nonsteroidal anti-inflammatory drugs (NSAID) class, but unlike many of its counterparts, it is not a corticosteroid or classic NSAID such…
1. Introduction Arava is a synthetic oral disease-modifying antirheumatic drug (DMARD) primarily indicated for the management of moderate to severe rheumatoid arthritis (RA). It is also used off-label in other inflammatory…
1. Introduction Sunitinib mesylate (Sutent®) is a multikinase inhibitor approved by the FDA and EMA for several advanced malignancies. It is classified as a targeted therapy, specifically a tyrosine kinase…
1. Drug Classification & Indications Dupixent (dupilumab) is a monoclonal antibody that selectively inhibits the interleukin-4 receptor alpha (IL-4Rα), thereby blocking signaling of both IL-4 and IL-13, two key cytokines…
1. Drug Classification & Mechanism of Action Alprazolam is a short-acting benzodiazepine, widely prescribed for the management of anxiety disorders and panic disorder. Benzodiazepines, including alprazolam, act as positive allosteric…
1. Overview and Chemical Profile Cyclopentolate hydrochloride ophthalmic solution (CPH) is a topical mydriatic and cycloplegic agent widely used in ophthalmology to induce pupil dilation (mydriasis) and paralysis of the…
What is ZERBAXA? ZERBAXA is a prescription antibiotic medication composed of two active ingredients: Ceftolozane: A next-generation cephalosporin antibiotic effective against a broad spectrum of Gram-negative bacteria, including multidrug-resistant strains…
What is Eylea? Eylea is a prescription medication that is used to treat wet age-related macular degeneration (AMD). Additionally, it is utilized to treat diabetic eye disease and other retinal…
Topamax (topiramate) was first licensed by the FDA as a seizure drug (also known as an anticonvulsant). Topiramate is a drug that is used to treat seizures in adults and…
CRESEMBA (Isavuconazonium sulfate) is a prescription medication used to treat specific forms of fungal infections in the blood or body known as \"aspergillosis\" and \"mucormycosis\" in adults 18 years of…
Age-Related Macular Degeneration (ARMD) is the most prevalent cause of visual impairment in people over the age of 50 in the Western world, and the leading cause of blind registration…
Introduction Harlequin ichthyosis (HI) is an exceptionally rare, autosomal recessive, genodermatosis characterized by profound abnormalities in epidermal barrier formation, leading to life-threatening complications in the neonatal period. It is the…
Definition & EpidemiologyToxic epidermal necrolysis (TEN) is a rare, life-threatening immune-mediated adverse drug reaction characterized by widespread apoptosis of keratinocytes leading to acute skin and mucosal detachment, resembling severe burn…
