arthritis

Medicine
Juvenile Idiopathic Arthritis (JIA): A Clinically Oriented Update Based on Current Evidence
Bydoctorcostamed July 5, 2022April 18, 2026
Prepared for the Practicing Rheumatologist / Pediatrician Definition & Epidemiology Juvenile Idiopathic Arthritis (JIA) is a heterogeneous group of chronic arthritides of unknown etiology onset before age 16, persisting ≥6 weeks. It represents an autoimmune/autoinflammatory condition with complex gene–environment interactions. Incidence: ~2–20 per 100,000 children/year; prevalence ~1 in 1,000 children in high-income countries (Hochberg et…
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Medicine
Nabumetone: Comprehensive Clinical Overview for Pharmacists
Bydoctorcostamed February 6, 2022April 18, 2026
1. Introduction and Classification Nabumetone is a member of the nonsteroidal anti-inflammatory drugs (NSAID) class, but unlike many of its counterparts, it is not a corticosteroid or classic NSAID such as ibuprofen or diclofenac. Instead, it is classified as a prodrug—a biologically inactive compound that undergoes hepatic metabolism to produce the active metabolite, 6-methoxy-2-naphthyl acetic…
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Medicine
What is gout? Symptoms, treatment, and complications.
ByCostaMedic May 25, 2020April 3, 2026
🔍 What Is Gout? Gout is the most common crystalline inflammatory arthritis, resulting from deposition of monosodium urate (MSU) crystals in joints and soft tissues; this typically occurs when serum uric acid exceeds ~6.8 mg/dL, exceeding crystallization thresholds OHSU+15PMC+15BioMed Central+15. The first metatarsophalangeal (MTP) joint (podagra) is affected in ~50% of cases. Gout flares are driven…
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