mosquito

Definition and Pathophysiology Skeeter syndrome (SS) is a rare, non-infectious, IgE-mediated Type I hypersensitivity reaction to proteins in mosquito saliva—specifically allergenic polypeptides such as Aedinae salivary gland antigen-2 (Aed a 2) and anticoagulant peptides. It manifests as an exaggerated local inflammatory response following mosquito bites, typically within 2–12 hours, although onset can be delayed up…