Comprehensive Clinical Review: Androgenetic Alopecia (AGA) in Males — Diagnosis, Pathophysiology, Workup, and Evidence-Based Management
I. Pathophysiology & Epidemiology: Core Clinical Concepts Androgenetic alopecia (AGA) is a genetically determined, androgen-dependent, nonscarring hair loss disorder affecting up to 50% of males by age 50 and >80% by age 70. It results from the interaction of androgens (particularly dihydrotestosterone [DHT]) with androgen receptor (AR) gene polymorphisms (e.g., AR on Xq12, PAX3 on…
