Comprehensive Clinical Update on Polycystic Kidney Disease: Pathophysiology, Diagnosis, Management, and Prognosis Based on Current Evidence
Prepared for the Practicing Clinician – Evidence-Based Overview with Emphasis on Clinical Decision-Making 1. Disease Classification and Genetic Basis Polycystic kidney disease (PKD) encompasses two major hereditary forms—autosomal dominant PKD (ADPKD) and autosomal recessive PKD (ARPKD)—differing significantly in inheritance pattern, age of onset, clinical severity, and molecular pathogenesis. A. Autosomal Dominant PKD (ADPKD) B. Autosomal…
