Comprehensive Clinical Overview of Grayson–Wilbrandt Corneal Dystrophy (GWCD): A Rare Autosomal Recessive Mitochondrial Disorder
1. Nomenclature & Classification Grayson–Wilbrandt Corneal Dystrophy (GWCD; OMIM #618546), often informally referred to as “Grayson’s Syndrome,” is a very rare, autosomal recessive corneal dystrophy classified under the mitochondrial subtype of corneal dystrophies in the International Classification of Corneal Dystrophies, 3rd edition (ICCD-3) [1]. It is distinct from nuclear envelope-related corneal dystrophies (e.g., REVERSI-type), and…
