varicose

Definition and EpidemiologyKlippel–Trenaunay syndrome (KTS; OMIM #150800) is a rare, non-hereditary congenital disorder characterized by a triad of features: Incidence is estimated at 1–5 per 100,000 live births, with no sex or ethnic predilection. KTS is considered a vascularOVERGROWTH spectrum disorder and is now classified under the broader entity PIK3CA-Related Overgrowth Spectrum (PROS), reflecting its…