Arava (Leflunomide): Comprehensive Clinical Overview
1. Introduction Arava is a synthetic oral disease-modifying antirheumatic drug (DMARD) primarily indicated for the management of moderate to severe rheumatoid arthritis (RA). It is also used off-label in other inflammatory arthritides such as psoriatic arthritis and certain forms of vasculitis. Its mechanism, safety profile, and complex pharmacokinetics require careful consideration by healthcare professionals. 2. Mechanism of…