Comprehensive Clinical Review: Glomerulonephritis — Pathophysiology, Classification, Diagnosis, Management, and Evidence-Based Considerations
Prepared for the practicing clinician — updated to reflect 2023–2024 guidelines from KDIGO, ASN, EULAR, and major randomized trials 1. Definition & Pathophysiological Basis Glomerulonephritis (GN) refers to a heterogeneous group of disorders characterized by inflammatory injury to the glomerular basement membrane (GBM), mesangium, or capillary walls, leading to impaired glomerular filtration, hematuria, proteinuria, and…