What is Celiac disease, signs, diet, diagnosis, and treatment
1. Definition and Core Pathophysiology: Beyond “Gluten Allergy” Celiac disease (CD) is a chronic, immune-mediated, systemic disorder triggered by ingestion of gluten and related proline-rich proteins (e.g., gliadin, secalin, hordein) in genetically susceptible individuals. It is not an IgE-mediated food allergy or simple intolerance. Key Immunopathogenic Steps (Mechanistic Insight for Clinical Correlation): Clinical Relevance: This…
