Clinical Monograph: Cytomegalovirus (CMV) Pathogenesis, Diagnosis, and Management
Overview Cytomegalovirus (CMV), a member of the Betaherpesvirinae subfamily (Human Betaherpesvirus 5), is a ubiquitous pathogen characterized by its ability to establish lifelong latency in mononuclear cells. While primary infection in immunocompetent hosts is often clinically silent or presents as a self-limiting mononucleosis-like syndrome, CMV remains a leading cause of morbidity and mortality in immunocompromised…