Tag: bone pain
Osteoporosis: Pathophysiology, Epidemiology, Diagnosis, and Management
IntroductionOsteoporosis is a systemic skeletal disorder characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and susceptibility to fracture (Cosman et al., Endocrine Reviews, 2014). The term—derived from the Greek osteon (bone) and poros (pore)—reflects the hallmark histological feature: reduced trabecular thickness and increased spacing between bone struts.…
Systemic juvenile rheumatoid arthritis
Overview Juvenile idiopathic arthritis (formerly known as systemic juvenile rheumatoid arthritis) is an umbrella term encompassing adolescent rheumatic disorders that begin before the age of 16 and are defined by joint inflammation that lasts for more than six weeks. On the basis of the pattern of joint involvement, the existence of extra-articular symptoms (such as…
