Crohn’s disease – Symptoms, Flair up, Diagnosis and TreatmentComprehensive Clinical Overview of Crohn’s Disease: Pathogenesis, Diagnosis, Management, and Contemporary Evidence-Based InsightsCrohn’s disease – Symptoms, Flair up, Diagnosis and Treatment
I. Definition and Epidemiology Crohn’s disease (CD) is a chronic, relapsing-remitting inflammatory bowel disease (IBD) characterized by transmural granulomatous inflammation that can affect any segment of the gastrointestinal (GI) tract—from mouth to anus—in a discontinuous, “skip lesions” pattern. Incidence: ~3–10 per 100,000 person-years in North America and Europe; prevalence rising globally, particularly in newly industrialized…
