Tag: cardiomyopathy
Hypertrophic Obstructive Cardiomyopathy (HOCM) – Symptoms, ECG, Murmur & Treatment
HCM is most often an autosomal dominant inherited heart muscle disease. The commonest pathogenic variants involve sarcomere-protein genes, especially MYH7 and MYBPC3, although other sarcomeric genes can also be involved. These variants lead to myocyte hypertrophy, myocyte disarray, fibrosis, impaired relaxation, ischemia, and a tendency to atrial and ventricular arrhythmias. It is important to separate…
