Category: Medicine
Ipilimumab – Indications, Dosage, and Side Effects
What is Ipilimumab? Ipilimumab is a humanized monoclonal antibody that targets CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), a key immune checkpoint receptor that downregulates immune activation. By blocking CTLA-4, ipilimumab enhances T-cell activation and proliferation, promoting an immune response against cancer cells. It is primarily used in combination with nivolumab (anti-PD-1 antibody) for treating various advanced…
Rosuvastatin – Indications, Dosage, and Side Effects
Introduction Rosuvastatin is a widely prescribed lipid-lowering agent belonging to the statin class. It is primarily used to improve lipid profiles by lowering low-density lipoprotein cholesterol (LDL-C), increasing high-density lipoprotein cholesterol (HDL-C), and reducing triglycerides, thereby reducing cardiovascular risk. Pharmacological Mechanism Rosuvastatin functions as a competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in hepatic…
Sofosbuvir – Indications, Dosage, and Side Effects
What is Sofosbuvir? Sofosbuvir was a ground-breaking new medication used to treat chronic hepatitis C patients. Sofosbuvir possesses a number of desirable characteristics, including once daily dosing, no meal restrictions, few adverse effects, few drug-drug interactions, a high genetic barrier to resistance, and relatively good safety and efficacy in patients with advanced liver disease. Sofosbuvir…
Dasatinib – Indications, and Side Effects
What is Dasatinib? Dasatinib is an anticancer drug. Dasatinib is used as a first-line treatment for a specific type of chronic myeloid leukemia (CML; a type of cancer of the white blood cells) in patients who no longer benefit from other leukemia medications, such as imatinib (Gleevec), or who are unable to take these medications…
Valcyte – Indications, Dosage, and Side Effects
What is Valcyte? Valcyte is approved for the treatment of cytomegalovirus (CMV) retinitis in adult patients with acquired immunodeficiency syndrome (AIDS). Valcyte is approved for the prevention of CMV infection in CMV-negative adults and children (birth to 18 years) who have undergone a solid organ donation from a CMV-positive donor. Valcyte uses Valganciclovir is a…
Bupivacaine – Indications, Dosage, and Side Effects
What is Bupivacaine? Bupivacaine, which is marketed under the brand names Marcaine and others, is a medication that is used to numb a specific area of the body. It is injected around a nerve that supplies the area or into the epidural space of the spinal canal in nerve blocks. Bupivacaine uses Bupivacaine injections are…
Riociguat – Indications, Dosage, and Side Effects
What is Riociguat? Riociguat is a Bayer-manufactured drug that acts as a stimulant of soluble guanylate cyclase. It is used to treat two types of pulmonary hypertension: chronic thromboembolic and pulmonary arterial hypertension. Riociguat is the first member of the sGC stimulator class of drugs. Riociguat uses Riociguat is used to treat adults who have…
Midol – Indications, Dosage, and Side Effects
What is Midol? Midol is a nonsteroidal anti-inflammatory medication (NSAID). Midol is a brand name for over-the-counter analgesics intended to treat period cramps and other menstrual-related symptoms. It inhibits the development of some natural compounds in your body that promote inflammation. If you have a chronic ailment such as arthritis, speak with your doctor about…
Xiaflex – Indications, Dosage, and Side Effects
What is Xiaflex? Xiaflex (collagenase clostridium histolyticum) is manufactured from a combination of proteins generated from a certain bacteria. Xiaflex uses Xiaflex is licensed by the U.S. Food and Drug Administration (FDA) for treatment of adults with Dupuytren\’s contracture and for adult men with Peyronie\’s illnesses with a palpable plaque and curvature deformity. It does…
Sitagliptin – Indications, Dosage, and Side Effects
What is Sitagliptin? Sitagliptin is a medication that is only available with a physician\’s prescription. It is available in the form of a tablet for oral administration. The brand-name medication Januvia contains sitagliptin oral tablet. There is no generic version available. Sitagliptin is sometimes used in combination with other medications. This may necessitate the use…