Comprehensive Overview of Hyperhidrosis: Physiology, Etiology, Diagnosis, and Evidence-Based Management
Physiology of Sweating Sweating—or perspiration—is a vital autonomic thermoregulatory function mediated primarily by eccrine sweat glands distributed across the skin. These glands are innervated by sympathetic cholinergic fibers, which release acetylcholine to stimulate sweat production in response to elevated core body temperature, emotional stress, or hormonal fluctuations. The primary purpose of sweating is to maintain…