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Tag: skin cancer
Keytruda (Pembrolizumab): A Comprehensive 2025 Clinical Overview
Keytruda® (generic: pembrolizumab) is a humanized monoclonal antibody that works as an immune checkpoint inhibitor, targeting PD-1 (programmed death-1) to restore anti-tumor immune responses. First approved by the FDA in 2014, it has since become a cornerstone in modern oncology across a wide array of solid and hematologic malignancies. 🧬 Mechanism of Action Pembrolizumab blocks…
Ipilimumab – Indications, Dosage, and Side Effects
What is Ipilimumab? Ipilimumab is a humanized monoclonal antibody that targets CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), a key immune checkpoint receptor that downregulates immune activation. By blocking CTLA-4, ipilimumab enhances T-cell activation and proliferation, promoting an immune response against cancer cells. It is primarily used in combination with nivolumab (anti-PD-1 antibody) for treating various advanced…
Basal Cell Carcinoma Vs Squamous Cell Carcinoma (BCC Vs SCC)
BCC and SCC Skin is the largest organ of the human body. Among all cancers, skin cancer is considered the most common cancer developed in humans. Â Cancer means abnormal growth and transformation of cells without having normal controls. As the cells multiply they form a tumor. Tumor means mass. They are called cancerous only…