Growth Hormone Deficiency (GHD): A Clinically Oriented Review
Epidemiology & Classification Key update (ES临床指南 2023, J Clin Endocrinol Metab): New data confirm transient GHD post-pituitary surgery in up to 30% of patients; hence, repeat testing at ≥3 months is mandatory before diagnosing permanent deficiency. Pathophysiology & Etiology A. In Children Category Examples Clinical Relevance Genetic GH1 (autosomal recessive), GHRHR (Dutch-type), PROP1 (most common familial cause; associated with delayed…