Clinical Review: Vitiligo (Leukoderma) – Pathophysiology, Diagnosis, and Evidence-Based Management
Note for Clinicians: While “leukoderma” is a general term for depigmentation, in clinical practice, it most commonly refers to Vitiligo. This review focuses on Vitilio as the primary differential diagnosis for acquired leukoderma. 1. Pathophysiology and Etiology Vitiligo is an acquired pigmentary disorder characterized by the progressive destruction of melanocytes within the basal layer of…