Comprehensive Review of Thalassemia: Pathophysiology, Classification, Diagnosis, Management, and Emerging Therapies—An Evidence-Based Update for Hematologists
Authored for the Hematology Community | Updated in Accordance with 2023–2024 Guidelines (ASH, EHA, WFH, NICE, Thalassaemia International Federation) 1. Introduction and Epidemiology Thalassemia is a group of inherited hemoglobinopathies characterized by reduced or absent synthesis of one or more globin chains, leading to imbalanced α:non-α globin chain ratio, ineffective erythropoiesis, hemolysis, and progressive anemia….
