fifth disease

Updated per current CDC, IDSA, and ECDC guidelines (2023–2024); evidence synthesized from peer-reviewed literature including New England Journal of Medicine, Clinical Infectious Diseases, Pediatrics, and The Lancet Infectious Diseases. Etiology & Epidemiology Fifth disease (erythema infectiosum) is a common, self-limited exanthem caused by human parvovirus B19 (B19V), a small, non-enveloped, single-stranded DNA virus in the…