EGPA

Overview & Definition Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg–Strauss syndrome (CSS), is a rare, systemic, necrotizing vasculitis affecting small-to-medium-sized blood vessels, characterized by: EGPA accounts for ~10–15% of all ANCA-associated vasculitides (AAV), with an estimated incidence of 1–3 cases per million per year. Median age at diagnosis is 45–50 years, though pediatric…