Diamond-Blackfan Anemia (DBA): Clinical Overview, Diagnostics, and Contemporary Management Strategies for Hematologists and Pediatric Specialists
Updated with Current Evidence (2023–2024 Guidelines and Landmark Studies) 1. Introduction and Pathophysiology Diamond-Blackfan Anemia (DBA; OMIM #105650) is a rare, inherited bone marrow failure syndrome (IBMFS) characterized by a selective defect in erythroid progenitor cell development, resulting in pure red cell aplasia—i.e., profoundFailure of erythropoiesis without significant involvement of myeloid or megakaryocytic lineages. DBA…
