blue man syndrome

Authored for Clinicians | Updated per 2023–2024 Guidelines & Literature Definition and Epidemiology Argyria (Greek argyros, “silver”) is a rare, irreversible dermal deposition disorder caused by chronic exposure to elemental silver (Ag⁰) or silver compounds (e.g., Ag⁺ salts), resulting in permanent blue–gray to slate–grey hyperpigmentation of the skin and mucous membranes. The term “Blue Man…