Anticoagulant

Introduction and Indications for Reversal Anticoagulation reversal is indicated in three primary clinical scenarios: The approach must integrate: I. Initial Assessment: Critical Diagnostic Steps A. Confirm Anticoagulant Exposure ⚠️ Pitfall: Routine PT/aPTT may be normal with therapeutic or supratherapeutic DOAC levels—especially apixaban (minimal aPTT prolongation). Always assume DOAC exposure if not proven otherwise in unexplained…